Her work takes a multi-disciplinary and collaborative approach that juxtaposes indigenous concepts and urban culture to bridge art and social justice praxis. She works with a range of media, including poetry, painting, live performance, and filmmaking.
Her literary work has been published on Luna Luna Magazine, Huizache: The Magazine of Latino Literature, Free Press Houston, Quiet Lunch Magazine Book. 2, The Panhandler Quarterly and MANGO Publications. Zelene founded of the Word Around Town Poetry Tour in 2005, and received Sor Juana Ines de la Cruz Young Visionary Award from The National Museum of Mexican Art in Chicago in 2009.